Glycated Hemoglobin, Diabetes, and Cardiovascular Risk in Nondiabetic Adults

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Glycated hemoglobin, diabetes, and cardiovascular risk in nondiabetic adults.

BACKGROUND Fasting glucose is the standard measure used to diagnose diabetes in the United States. Recently, glycated hemoglobin was also recommended for this purpose. METHODS We compared the prognostic value of glycated hemoglobin and fasting glucose for identifying adults at risk for diabetes or cardiovascular disease. We measured glycated hemoglobin in whole-blood samples from 11,092 black...

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OBJECTIVE Glycated hemoglobin was recently recommended for use as a diagnostic test for diabetes. We examined the association between 2010 American Diabetes Association diagnostic cut points for glycated hemoglobin and microvascular outcomes (chronic kidney disease, end-stage renal disease [ESRD], and retinopathy) and formally tested for the presence of risk thresholds in the relationships of g...

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Low Hemoglobin A1c in Nondiabetic Adults

OBJECTIVE To identify predictors of low hemoglobin A(1c) (HbA(1c)) (<5.0%) and to investigate the association of low HbA(1c) with cause-specific mortality and risk of liver disease hospitalization. RESEARCH DESIGN AND METHODS Prospective cohort study of 13,288 participants in the Atherosclerosis Risk in Communities Study. Logistic regression was used to identify cross-sectional correlates of ...

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ژورنال

عنوان ژورنال: New England Journal of Medicine

سال: 2010

ISSN: 0028-4793,1533-4406

DOI: 10.1056/nejmoa0908359